NIPP1 (PPP1R8) Mouse Monoclonal Antibody [Clone ID: OTI1E9]

CAT#: CF804571

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Carrier-free (BSA/glycerol-free) Purified PPP1R8 mouse monoclonal antibody, clone OTI1E9 (formerly 1E9)



  View other "OTI1E9" antibodies (4)

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USD 495.00


Availability*
In Stock

Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI1E9
Applications WB
Recommended Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-225 of human PPP1R8 (NP_612568) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 22.5 kDa
Gene Name Homo sapiens protein phosphatase 1 regulatory subunit 8 (PPP1R8), transcript variant 2, mRNA.
Background This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul
Synonyms ARD-1; ARD1; NIPP-1; NIPP1; PRO2047
Reference Data
Protein Families Druggable Genome, Transcription Factors

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