Ornithine Carbamoyltransferase (OTC) Mouse Monoclonal Antibody [Clone ID: OTI4G8]

CAT#: CF802596

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Carrier-free (BSA/glycerol-free) OTC mouse monoclonal antibody, clone OTI4G8 (formerly 4G8)



  View other "OTI4G8" antibodies (4)

USD 465.00


Availability*
In Stock

Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI4G8
Applications IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human, Mouse, Rat
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 33-354 of human OTC (NP_000522)produced in SF9 cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 36.1 kDa
Gene Name Homo sapiens ornithine carbamoyltransferase (OTC), mRNA.
Background This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq, Jul 2008]
Synonyms OCTD
Reference Data
Protein Families Druggable Genome
Protein Pathways Arginine and proline metabolism, Metabolic pathways

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