SEN1 (MORF4) Mouse Monoclonal Antibody [Clone ID: OTI5E6]

CAT#: CF800387

Carrier-free (BSA/glycerol-free) MORF4 mouse monoclonal antibody, clone OTI5E6 (formerly 5E6)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MORF4 ([RC217344], Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MORF4.

Specifications

Product Data

• Clone Name: OTI5E6
• Applications: WB
• Recommended Dilution: WB: 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-255 of human MORF4 (NP_006783) produced in E.coli.
• Formulation: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 26.6 kDa
• Gene Name: mortality factor 4 (pseudogene)
• Database Link:
  NP_006783
  Entrez Gene 10934 Human
• Background: Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to 1 of several complementation groups. MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B. [supplied by OMIM]
• Synonyms: CSR; CSRB; mortality factor 4; SEN; SEN1; senescence (cellular)-related 1; senescence-related, cellular, 1

Reference Data

• Protein Families: Transcription Factors