MMP13 Mouse Monoclonal Antibody [Clone ID: OTI3F5]

CAT#: CF506721

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Carrier-free (BSA/glycerol-free) MMP13 mouse monoclonal antibody, clone OTI3F5 (formerly 3F5)



  View other "OTI3F5" antibodies (4)

USD 545.00


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Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI3F5
Applications IHC, WB
Recommended Dilution WB 1:4000, IHC 1:150
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 104-471 of human MMP13 (NP_002418) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 42.2 kDa
Gene Name Homo sapiens matrix metallopeptidase 13 (MMP13), mRNA.
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Synonyms CLG3; MANDP1; MDST; MMP-13
Reference Data
Protein Families Druggable Genome, Protease

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