Cytochrome P450 17A1(CYP17A1) Mouse Monoclonal Antibody [Clone ID: OTI5G10]

CAT#: CF503415

Carrier-free (BSA/glycerol-free) CYP17A1 mouse monoclonal antibody, clone OTI5G10 (formerly 5G10)

 Product Datasheet for 'CF503415'

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USD 450.00

4 Weeks

    • 100 ug

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Product Data
Clone Name OTI5G10
Applications WB
Recommend Dilution WB 1:2000,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CYP17A1(NP_000093) produced in HEK293T cell.
Isotype IgG1
Formulation PBS (pH7.3), 8% Trehalose
Reconstitution Method Reconstitute with PBS (pH7.3). To use this carrier-free antibody for conjugation experiment, we strongly recommend you to perform another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 57.2 kDa
Gene Name Homo sapiens cytochrome P450 family 17 subfamily A member 1 (CYP17A1)
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq].
Synonyms CPT7; CYP17; P450C17; S17AH
Reference Data
Protein Families P450, Druggable Genome
Protein Pathways C21-Steroid hormone metabolism, Metabolic pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.