AP2M1 Mouse Monoclonal Antibody [Clone ID: OTI1E9]

CAT#: CF503019

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Carrier-free (BSA/glycerol-free) AP2M1 mouse monoclonal antibody, clone OTI1E9 (formerly 1E9)



  View other "OTI1E9" antibodies (4)

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USD 495.00


Availability*
4 Weeks

Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI1E9
Applications IF, IHC, WB
Recommended Dilution WB 1:200~500, IHC 1:150, IF 1:100
Reactivity Human, Monkey, Mouse, Rat, Dog
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 97-383 of human AP2M1(NP_001020376) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 49.2 kDa
Gene Name Homo sapiens adaptor related protein complex 2 subunit mu 1 (AP2M1), transcript variant 2, mRNA.
Background This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms AP50; CLAPM1; mu2
Reference Data
Protein Families Druggable Genome
Protein Pathways Endocytosis, Huntington's disease

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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