Haptoglobin (HP) Mouse Monoclonal Antibody [Clone ID: OTI4H5]
SKU
CF501699
Carrier-free (BSA/glycerol-free) HP mouse monoclonal antibody, clone OTI4H5 (formerly 4H5)
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TrueMAB™
Antibodies made against full-length proteins as antigens.
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Product Data | |
Clone Name | OTI4H5 |
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Application | FC, IF, WB |
Recommended Dilution | WB 1:500, IF 1:100, FLOW 1:100 |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human HP (NP_005134) produced in HEK293T cell. |
Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Ambient |
Predicted Protein Size | 43.3 kDa |
Gene Name | haptoglobin |
Database Link | |
Background | This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Synonyms | BP; HP2ALPHA2; HPA1S |
Reference Data | |
Protein Families | Druggable Genome, Protease, Secreted Protein, Transmembrane |
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Product Manuals |
FAQs |
SDS |
Antibody Resources |
SKU | Description | Size | Price | |
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TA501699 | Anti-HP mouse monoclonal antibody, clone OTI4H5 (formerly 4H5) | 100 ul |
$447.00
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TA501699AM | HP mouse monoclonal antibody, clone 4H5, Biotinylated | 100 ul |
$509.00
|
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TA501699BM | HP mouse monoclonal antibody, clone 4H5, HRP conjugated | 100 ul |
$509.00
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TA501699S | Anti-HP mouse monoclonal antibody, clone OTI4H5 (formerly 4H5) | 30 ul |
$200.00
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.