TRPM4 Mouse Monoclonal Antibody [Clone ID: OTI10H5]

CAT#: CF500381

Reviews ()
Write a review

Carrier-free (BSA/glycerol-free) TRPM4 mouse monoclonal antibody, clone OTI10H5 (formerly 10H5)


 Product Datasheet for 'CF500381'

  View other "OTI10H5" antibodies (2)

USD 465.00


Availability*
4 Weeks

Size
    • 100 ug


Specifications

Product Data
Clone Name OTI10H5
Applications IHC, WB
Recommend Dilution WB 1:5000~10000, IHC 1:50
Reactivity Human, Monkey, Dog
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human TRPM4 (NP_060106) produced in HEK293T cell.
Formulation PBS (pH7.3), 8% Trehalose
Reconstitution Method Reconstitute with PBS (pH7.3). To use this carrier-free antibody for conjugation experiment, we strongly recommend you to perform another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 134.3 kDa
Gene Name Homo sapiens transient receptor potential cation channel subfamily M member 4 (TRPM4), transcript variant 1
Background Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload.
Synonyms hTRPM4; LTrpC4; PFHB1B; TRPM4B
Reference Data
Protein Families Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane

Other Versions

Other products for "TRPM4"
Frequently bought together (2)
Biotinylation Labelling Kit formatted 4 x 0.05mg
    • 200 ug

USD 350.00


HRP Conjugation kit for 0.2mg IgG
    • 200 ug

USD 225.00

Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Antibody Performance Guarantee banner
ANTIBODY VALIDATION 101
BOGO Free lysates
68 Mouse Clones