TRPM4 Mouse Monoclonal Antibody [Clone ID: OTI3C4]
SKU
CF500370
Carrier-free (BSA/glycerol-free) TRPM4 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4)
$620.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI3C4 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full-length protein expressed in 293T cell transfected with human TRPM4 expression vector |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 134.3 kDa |
| Gene Name | transient receptor potential cation channel subfamily M member 4 |
| Database Link | |
| Background | Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload |
| Synonyms | hTRPM4; LTrpC4; PFHB1B; TRPM4B |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Cytokines, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3C4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA500370 | Anti-TRPM4 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4) | 100 ul |
$447.00
|
|
| TA500370AM | Anti-TRPM4 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4), Biotinylated | 100 ul |
$509.00
|
|
| TA500370BM | Anti-TRPM4 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4), HRP conjugated | 100 ul |
$509.00
|
|
| TA500370S | Anti-TRPM4 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
