Tenascin C (TNC) Mouse Monoclonal Antibody [Clone ID: T2H5]

CAT#: BM722S

Tenascin C (TNC) mouse monoclonal antibody, clone T2H5, Purified

Product Images

Immunohistochemistry staining of tonsil (paraffin-embedded sections) with anti-human Tenascin (T2H5).

Specifications

Product Data

• Clone Name: T2H5
• Applications: IHC, IP, WB
• Recommended Dilution: Western Blotting.1-2 μg/ml.
  Immunoprecipitation.
  Immunohistochemistry on Paraffin Sections: Immunohistochemical detection of Tenascin is valuable for studies of tissue differentiation and tumour growth.
  The antibody T2H5 is excellent for staining of paraffin-embedded tissue sections.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Protein preparation from a homogenate of a Human mammary tumour specimen.
• Specificity: The antibody recognizes Tenascin, a large hexameric extracellular matrix glycoprotein.
• Formulation: Phosphate buffered saline (PBS), pH~7.4
  State: Purified
  State: Liquid purified Ig fraction from Hybridoma Culture Supernatant (> 95% pure by SDS-PAGE)
  Preservative: 15 mM Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  
• Stability: Shelf life: one year from despatch.
• Gene Name: tenascin C
• Database Link:
  Entrez Gene 3371 Human
  UniProt ID P24821
• Background: Tenascin is a high molecular ECM glycoprotein (MW app. 210-300 kDa), which contains hexamere repeat-rich single chains. It contains EGF-, Fibronectin III- and Fibronectin-similar structures. During organogenesis it is exprimed temporarily by many organs. During adulthood it reappears only in regeneration, wound healing and in stroma of various tumours. It probably has an anti-adhesive function, which plays a role during tumour speading. Tenascin is found in the central and peripheral nerve system, in smooth muscle, tendon and hyper-proliferative skin.
• Synonyms: Tenascin-C, TN-C, Hexabrachion, Cytotactin, Neuronectin, GMEM