Lipoprotein lipase (LPL) Mouse Monoclonal Antibody [Clone ID: Mab-7]

CAT#: BM5512

Lipoprotein lipase (LPL) mouse monoclonal antibody, clone Mab-7, Purified

Specifications

Product Data

• Clone Name: Mab-7
• Applications: ELISA, FN, IHC, WB
• Recommended Dilution: ELISA.
  Immunoblotting.
  Immunohistochemistry.
  Recommended Dilutions: 1/10.
  Dilution buffer: PBS with 0.5 % BSA and 0.09% Sodium Azide.
• Reactivities: Bovine, Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified Bovine Lipoprotein Lipase
• Specificity: This Monoclonal antibody is directed against the CII binding site.
  Blocks the catalytic activity of Bovine milk lipase.
  A small partial cross-reactivity with Human Heparin Plasma Lipase activity was observed (Ref. 1).
• Formulation: PBS, pH 7.4
  State: Purified
  State: Lyophilized purified IgG fraction
  Stabilizer: 0.5% BSA
  Preservative: 0.09% Sodium Azide
• Reconstitution Method: Restore with 1 ml distilled water
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: lipoprotein lipase
• Database Link:
  Entrez Gene 4023 Human
  UniProt ID P06858
• Background: Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.
• Synonyms: LPL, LIPD, EC=3.1.1.34