Hepatitis B Surface Antigen / HBsAg (adw) Mouse Monoclonal Antibody [Clone ID: S26]
CAT#: BM3262
Hepatitis B Surface Antigen / HBsAg (adw) mouse monoclonal antibody, clone S26, Azide Free
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Specifications
Product Data | |
Clone Name | S26 |
Applications | ELISA, EM, IF, IHC, WB |
Recommended Dilution | Suitable for use in Immunofluorescent and immunoperoxidase staining, Western blot, ELISA and Immuno electron microscopy. |
Reactivities | Hepatitis B Virus |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | HBsAg from human sera pool. |
Specificity | HBsAg pre-S2 antigen (a.a. 132-137) (adw nomenclature). Reference start codon was Pre-S1. Epitope recognition confirmed by competing with peptides. |
Formulation | PBS, pH 7.4 without preservative. State: Azide Free State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Protein A affinity chromatography. |
Conjugation | Unconjugated |
Storage | Store the antibody at 2-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Background | Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction. |
Synonyms | HBV surface antigen, Hepatitis B Virus |
Reference Data |
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