IKK gamma (IKBKG) pSer31 Rabbit Polyclonal Antibody
IKK gamma (IKBKG) pSer31 rabbit polyclonal antibody, Aff - Purified
|Recommended Dilution||Western blot: 1:500~1:1000.|
|Immunogen||Peptide sequence around phosphorylation site of serine 31 (E-E-S(p)-P-L) derived from Human IKK-gamma (KLH-conjugated)|
|Specificity||The antibody detects endogenous level of IKK- gamma only when phosphorylated at serine 31.|
|Formulation||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
|Purification||Affinity chromatography using epitope-specific peptide|
|Storage||Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
|Stability||Shelf life: one year from despatch.|
|Predicted Protein Size||48 kDa|
|Background||Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly.|
|Synonyms||FIP3, FIP-3, IKKAP1, I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.