IKK gamma (IKBKG) pSer31 Rabbit Polyclonal Antibody

CAT#: AP55918PU-S

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IKK gamma (IKBKG) pSer31 rabbit polyclonal antibody, Aff - Purified

USD 312.00

2 Weeks

    • 50 ul

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Product Data
Applications WB
Recommended Dilution Western blot: 1:500~1:1000.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of serine 31 (E-E-S(p)-P-L) derived from Human IKK-gamma (KLH-conjugated)
Specificity The antibody detects endogenous level of IKK- gamma only when phosphorylated at serine 31.
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Predicted Protein Size 48 kDa
Background Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly.
Synonyms FIP3, FIP-3, IKKAP1, I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma
Reference Data
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