ZCRB1 (C-term) Rabbit Polyclonal Antibody
ZCRB1 (C-term) rabbit polyclonal antibody, Aff - Purified
Product Datasheet for 'AP54628PU-N'
|Recommend Dilution||Immunohistochemistry on paraffin sections: 1:10~50.
Western blot: 1:100~500.
|Immunogen||KLH conjugated synthetic peptide between 183-212 amino acids from the C-terminal region of human ZCRB1|
|Specificity||This antibody detects ZCRB1 (C-term).|
|Formulation||PBS with 0.09% (W/V) sodium azide
State: Aff - Purified
State: Liquid Ig fraction
|Purification||Protein A column followed by peptide affinity purification|
|Gene Name||Homo sapiens zinc finger CCHC-type and RNA binding motif containing 1 (ZCRB1)|
|Background||Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.|
|Synonyms||MADP-1; MADP1; MGC26805; RBM36; U11; U12-31K; ZCCHC19|
|Note||Molecular Weight: 24592 Da|
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