BCMA (TNFRSF17) (Center) Rabbit Polyclonal Antibody

CAT#: AP54310PU-N

BCMA (TNFRSF17) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

TNFRSF17 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35 ug/lane). This demonstrates the TNFRSF17 antibody detected the TNFRSF17 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 62-92 amino acids from the Central region of human TNFRSF17
• Specificity: This antibody detects CD269 / BCMA (Center).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens TNF receptor superfamily member 17 (TNFRSF17)
• Database Link:
  Entrez Gene 608 Human
  UniProt ID Q02223
• Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
• Synonyms: TNFRSF17, BCM
• Note: Molecular Weight: 20165 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction