S100 beta (S100B) Rabbit Polyclonal Antibody

CAT#: AP53778PU-N

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Rabbit Polyclonal Anti-S100B Antibody, Aff - Purified


 Product Datasheet for 'AP53778PU-N'

USD 415.00


Availability*
2 Weeks

Size
    • 400 ul


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Specifications

Product Data
Applications WB
Recommend Dilution IHC, WB
Reactivity Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide from human S100B/S-100; central epitope
Formulation PBS with 0.09% (W/V) Sodium Azide as preservative
Concentration lot specific
Purification Protein A column followed by peptide affinity purification
Predicted Protein Size 10.5 kDa
Gene Name S100 calcium binding protein B
Background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Synonyms NEF; S100; S100-B; S100beta
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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