PLA2G12A (Center) Rabbit Polyclonal Antibody

CAT#: AP53322PU-N

PLA2G12A (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PLA2G12A Antibody (Center) in A2058 cell line lysates (35ug/lane). This demonstrates the PLA2G12A antibody detected the PLA2G12A protein (arrow).

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  Western blot analysis of PLA2G12A (arrow) using PLA2G12A Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PLA2G12A gene.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 54-83 amino acids from the Central region of human PLA2G12A
• Specificity: This antibody recognizes Human PLA2G12A (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: phospholipase A2 group XIIA
• Database Link:
  Entrez Gene 81579 Human
  UniProt ID Q9BZM1
• Background:
  Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).
• Synonyms: Phospholipase A2 group XIIA, PLA2G12, GXII sPLA2, sPLA2-XII
• Note: Molecular Weight: 21067 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway