Protocadherin beta 13 (PCDHB13) (Center) Rabbit Polyclonal Antibody

CAT#: AP53208PU-N

Protocadherin beta 13 (PCDHB13) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in MDA-MB435 cell line lysates (35ug/lane) using PCDHB13 antibody. This demonstrates the PCDHB13 antibody detected the PCDHB13 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blot: 1/100-1/500.
  Enzyme immunoassay: 1/1000.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 280-308aa) of human PCDHB13.
• Specificity: This antibody recognizes PCDHB13.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: protocadherin beta 13
• Database Link:
  Entrez Gene 56123 Human
  UniProt ID Q9Y5F0
• Background: The PCDHB13 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
• Synonyms: Protocadherin beta-13, PCDH-beta-13
• Note: Molecular Weight: 87552 Da

Reference Data

• Protein Families: Transmembrane