MCAF2 (ATF7IP2) (Center) Rabbit Polyclonal Antibody
Product Data | |
Application | FC, IHC, WB |
---|---|
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. Flow Cytometry: 1/10-1/50. Immunohistochemistry on Paraffin Sections: 1/50-1/100. |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 325-355 amino acids from the Central region of human MCAF2 |
Specificity | This antibody recognizes Human and Mouse MCAF2 (Center). |
Buffer | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | activating transcription factor 7 interacting protein 2 |
Database Link | |
Background | Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable). |
Synonyms | Activating transcription factor 7-interacting protein 2, MCAF2, MBD1-containing chromatin-associated factor 2 |
Note | Molecular Weight: 75764 Da |
Reference Data |
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