EGF (Center) Rabbit Polyclonal Antibody

CAT#: AP51384PU-N

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EGF (Center) rabbit polyclonal antibody, Aff - Purified


 Product Datasheet for 'AP51384PU-N'

USD 450.00


Availability*
2 Weeks

Size
    • 400 ul


Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution ELISA:  1/1000.
Western Blot: 1/100 - 1/500.
Reactivity Human, Mouse
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 689-720 amino acids from the Central region of human EGF
Specificity This antibody reacts to EGF.
Formulation PBS
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.09% (W/V) sodium azide
Concentration lot specific
Purification Affinity chromatography on Protein A
Predicted Protein Size 133994 Da
Gene Name Homo sapiens epidermal growth factor (EGF), transcript variant 1
Background This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
Synonyms Urogastrone, Epidermal growth factor, URG, HOMG4
Reference Data
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane
Protein Pathways Bladder cancer, Cytokine-cytokine receptor interaction, Endocytosis, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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ANTIBODY VALIDATION 101
68 Mouse Clones