LINC02210-CRHR1 Rabbit Polyclonal Antibody

CAT#: AP51078PU-N

LINC02210-CRHR1 rabbit polyclonal antibody, Aff - Purified

Product Images

CRFR1 Antibody western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CRFR1 antibody detected the CRFR1 protein (arrow).

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  CRFR1 Antibody (Q103) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
  Flow Cytometry: 1/10 - 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 95-128 amino acids from human CRHR1
• Specificity: This antibody reacts to human CRFR1.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 50719 Da
• Gene Name: LINC02210-CRHR1 readthrough
• Database Link:
  Entrez Gene 1394 HumanEntrez Gene 104909134 Human
  UniProt ID P34998
• Background: This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants.
• Synonyms: CRHR-1, CRFR, CRFR1, CRHR, Corticotropin-releasing factor receptor 1, CRF-R, CRF1, Corticotropin-releasing hormone receptor 1, CRH-R 1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Long-term depression, Neuroactive ligand-receptor interaction