CHADL (Center) Rabbit Polyclonal Antibody

CAT#: AP50883PU-N

CHADL (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

CHADL Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the CHADL antibody detected the CHADL protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 405-434 amino acids from the Central region of human CHADL
• Specificity: This antibody reacts to CHADL.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: Isoform2 74kd. 82388 Da
• Gene Name: chondroadherin like
• Database Link:
  Entrez Gene 150356 Human
  UniProt ID Q6NUI6
• Background: Members of the small leucine-rich proteoglycan (SLRP) family are mostly extracellular proteins that function upstream of multiple signaling cascades. They affect intracellular phosphorylation and modulate distinct pathways, such as those driven by Toll-like receptors, TGF? and receptor tyrosine kinases. As a member of the SLRP family, CHADL (Chondroadherin-like protein) is a 762 amino acid protein containing 21 LRR (leucine-rich) repeats, which promote protein-ligand interactions. Chondroadherin, a closely related protein, promotes attachment of chrondocytes, osteoblasts and fibroblasts and also plays an important role in the regulation of chrodrocyte proliferation and growth. CHADL is a secreted protein that is located in the extracellular space. There are two isoforms of CHADL that exist as a result of alternative splicing events.
• Synonyms: Chondroadherin-like protein,SLRR4B