AMACR (C-term) Rabbit Polyclonal Antibody

CAT#: AP50158PU-N

AMACR (C-term) rabbit polyclonal antibody, Aff - Purified


USD 560.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications FC, IF, IHC, WB
Recommended Dilution ELISA: 1/1000.
Western blotting: 1/100 - 1/500.
Immunohistochemistry: 1/50 - 1/100.
Flow Cytometry: 1/10 - 1/50.
Immunofluorescence: 1710 - 1/50.
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 330-359 amino acids from the C-terminal region of human AMACR
Specificity This antibody reacts to AMACR.
Formulation PBS with 0.09% (W/V) sodium azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity chromatography on Protein A
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1
Background This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
Synonyms Alpha-methylacyl-CoA racemase, P504S
Note Molecular Weight: 42387 Da
Reference Data
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Primary bile acid biosynthesis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.