ACAT1 Rabbit Polyclonal Antibody

CAT#: AP31747PU-N

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ACAT1 rabbit polyclonal antibody, Aff - Purified



USD 440.00


Availability*
2 Weeks

Size
    • 50 ul


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Specifications

Product Data
Applications IHC, WB
Recommended Dilution Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
Western Blot: 1/1000 - 1/4000.
Reactivity Human, Mouse, Porcine, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide
Specificity This Polyclonal antibody is directed against Human ACAT1 protein.
Cross-reactivity with ACAT1 from other sources has not been determined.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration 1 mg/ml
Purification Affinity Chromatography on Protein A
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens acetyl-CoA acetyltransferase 1 (ACAT1)
Background ACAT1 mRNA encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. The ACAT gene spans approximately 27 kb and contains 12 exons interrupted by 11 introns. Defects in this gene are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
Synonyms ACAT; MAT; T2; THIL
Reference Data
Protein Families Druggable Genome
Protein Pathways Butanoate metabolism, Fatty acid metabolism, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Tryptophan metabolism, Valine, leucine and isoleucine degradation
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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