Rabbit Polyclonal Antibody
Rabbit Polyclonal anti-Substance P Antibody
Product Datasheet for 'AP31320SU-N'
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|Immunogen||Synthetic Substance P coupled to KLH.|
|Background||Substance P occurs in nerve fibers of the central and peripheral nervous system and in endocrine cells of the gut. Substance P containing nerve fibers in the gut wall are particularly numerous in the myenteric plexus and the smooth muscle layers. Substance P containing tumors arising in the ileum are often associated with the "carcinoid syndrome", characterized by flushing of the skin, diarrhea, bronchoconstriction and sudden drops in blood pressure. Substance P is commonly found in midgut carcinoids and some of the symptoms may be related to this peptide.|