CD51 (ITGAV) (C-term) Rabbit Polyclonal Antibody
CD51 (ITGAV) (C-term) rabbit polyclonal antibody, Purified
|Applications||ELISA, IHC, WB|
|Recommend Dilution||ELISA: 1/10000.
Immunohistochemistry on Paraffin Sections: 1/200.
Western Blot: 1/500 - 1/1000.
|Immunogen||ITGAV antibody was raised against synthetic peptide|
|Specificity||This antibody reacts to ITGAV / CD51.|
|Formulation||PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
State: Liquid purified Ig fraction
|Gene Name||Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 3|
|Background||ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction.|
|Synonyms||Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha|
|Protein Families||Druggable Genome, ES Cell Differentiation/IPS, Transmembrane|
|Protein Pathways||Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.