CD51 (ITGAV) (C-term) Rabbit Polyclonal Antibody

CAT#: AP31171PU-N

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CD51 (ITGAV) (C-term) rabbit polyclonal antibody, Purified

Product Datasheet for 'AP31171PU-N'

USD 440.00

2 Weeks

    • 50 ul

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Product Data
Applications ELISA, IHC, WB
Recommend Dilution ELISA: 1/10000.
Immunohistochemistry on Paraffin Sections: 1/200.
Western Blot: 1/500 - 1/1000.
Reactivity Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen ITGAV antibody was raised against synthetic peptide
Specificity This antibody reacts to ITGAV / CD51.
Formulation PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration 1,0 mg/ml
Purification Immunoaffinity chromatography
Gene Name Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 3
Background ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction.
Synonyms Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer
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68 Mouse Clones