KCNK2 (4-14) Rabbit Polyclonal Antibody
KCNK2 (4-14) rabbit polyclonal antibody, Azide Free
|Recommended Dilution||ELISA: The antibody (1:500,000 diluted) can detect the TREK-1 peptide coated on ELISA plate at 100ng/well.
Western blot: Dilute approx. 1:3,000 to detect the 47kDa TREK-1 in Jurkat cell extract.
|Immunogen||A synthetic peptide derived from the amino sequence 4-14 of human TREK-1, conjugated with KLH|
|Specificity||This antibody reacts with the 47kDa TREK-1 in Jurkat cell extract.|
|Formulation||0.01M PBS, pH 7.4
State: Azide Free
State: Lyophilized Ig fraction
|Reconstitution Method||Restore with double distilled water to adjust the final concentration to 1.00 mg/ml.|
|Purification||Protein G affinity|
|Storage||Store lyophilized at 2-8°C for 6 month or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
|Stability||Shelf life: one year from despatch.|
|Background||TWIK-related potassium channel 1(TREK-1), also known as K2P2.1, is a two pore domain gated potassium channel that is involved with pain reception. TREK-1 is highly expressed in small sensory neurons and is extensively colocalized with TRPV1. TREK-1 is sensitive to noxious stimuli including extracellular pH, temperature, mechanical force, osmotic pressure and other stimuli. TREK-1 is one of the targets for pain mediator and anaesthesia drug.|
|Synonyms||KCNK2, TREK, TREK1, Potassium channel subfamily K member 2, Two pore potassium channel TPKC1|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.