IKK gamma (IKBKG) pSer31 Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA |
Recommended Dilution | ELISA: The antibody (approx. 1:100,000 – 1:400,000 diluted) can detect the Ser31 phosphorylated IkK-γ peptide coated on ELISA plate. |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic peptide derived from Serine 31 phosphorylated IKK-γ, conjugated with KLH |
Specificity | This antibody detects Serine 31 phosphorylated IKK-γ from Human and other species with peptide LGEESpPLGKPA. |
Formulation | PBS, pH 7.4, 0.01M PBS State: Azide Free State: Lyophilized Ig fraction |
Reconstitution Method | Restore with double distilled water to adjust the final concentration to 1.00mg/ml. |
Purification | Protein G affinity |
Conjugation | Unconjugated |
Storage | Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma |
Database Link | |
Background | IKK-γ is the γ subunit in the IκB kinase (Ikk) complex, also referred to as NF-κB essential modulator isoform c. IKK plays an important role in the NF-κB signal transduction pathway by phosphorylating IκB a subunit and disassociating NF-κB from IκB in cytoplasma. Thus, NF-κB is released and migrates to nucleus to activate the transcription of many genes that are involved with immuno-response, cell survival, and neuroplasticity. |
Synonyms | FIP3, FIP-3, IKKAP1, I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma |
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