HIP2 (UBE2K) Goat Polyclonal Antibody

CAT#: AP23819PU-N

Goat Polyclonal Anti-UBE2K Antibody, Purified


 Product Datasheet for 'AP23819PU-N'

USD 425.00


Availability*
2 Weeks

Size
    • 50 ug


Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution ELISA, IHC, WB
Reactivity Human
Host Goat
Clonality Polyclonal
Immunogen Synthetic peptide (C-SWDVETATELLLSN) from C-terminus of human HIP2
Formulation Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
Concentration 0,5 mg/ml
Purification Immunoaffinity Chromatography
Predicted Protein Size 22.2 kDa
Gene Name ubiquitin conjugating enzyme E2 K
Background The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Synonyms E2-25K; HIP2; HYPG; LIG; UBC1
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Ubiquitin mediated proteolysis
Other products for "UBE2K"
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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