Cytochrome C (CYCS) (C-term) Rabbit Polyclonal Antibody

CAT#: AP23373PU-N

Cytochrome C (CYCS) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Paraffi Rat Lung Tissue stained with Cytochrome C Polyclonal Antibody

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: At 0.1-0.5 μg/ml with the appropriate system to detect Cytochrome C in cells and tissues.
  Immunohistochemistry on Paraffin Sections: At 0.5-1 μg/ml to detect Cytochrome C in formalin fixed and paraffin embedded tissues.
  Immunohistochemistry on Frozen Sections: At 0.5-1 μg/ml to detect Cytochrome C in formalin or acetone fixed tissues.
  Immunocytochmeistry: 1 µg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a sequence at the C-terminal of human Cytochrome C
• Specificity: This antibody detects Cytochrome c (C-term, 91-105). No cross reactivity with other proteins.
• Formulation: 0.9mg NaCl, 0.2mg Na2HPO4
  State: Aff - Purified
  State: Lyophilized Ig fraction
  Stabilizer: 5mg BSA
  Preservative: 0.05mg Thimerosal, 0.05mg Sodium Azide
• Reconstitution Method: 0.2ml of distilled water will yield a concentration of 500μg/ml.
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: cytochrome c, somatic
• Database Link:
  Entrez Gene 13063 MouseEntrez Gene 25309 RatEntrez Gene 54205 Human
  UniProt ID P99999
• Background: Cytochrome C is located in the mitochondria of all aerobic cells and is involved in the electron transport system. Human cytochrome c has 104 amino acid residues and a molecular weight of 11,458 and is mapped to 7p15.2. Cytochrome c released from mitochondria has been proposed to be an essential component of an apoptotic pathway responsive to DNA damage and other forms of cell stress. And it has a role in different apoptotic signaling cascades.
• Synonyms: CYCS, CYC

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Huntington's disease, p53 signaling pathway, Parkinson's disease, Pathways in cancer, Small cell lung cancer, Viral myocarditis