MIF (C-term) Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
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Recommended Dilution | Western blot: At 1-2μg/ml with the appropriate system to detect MIF in cells and tissues. Immunohistochemistry on paraffin sections: At 1-2μg/ml to detect MIF in formalin fixed and paraffin embedded tissues. |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a sequence at the C-terminal of human MIF |
Specificity | This antibody detects MIF at C-term. No cross reactivity with other proteins. |
Buffer | 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 State: Aff - Purified State: Lyophilized Ig fraction |
Reconstitution Method | 0.2ml of distilled water will yield a concentration of 500μg/ml. |
Purification | Immunogen affinity purified |
Conjugation | Unconjugated |
Storage | Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Ambient |
Gene Name | macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
Database Link | |
Background | Macrophage migration inhibitory factor, MIF, is a cytokine released by T-lymphocytes, macrophages,and the pituitary gland that serves to integrate peripheral and central inflammatory responses. MIF gene has 3 exons separated by introns of only 189 and 95 bp, and covers less than 1 kb. Localization of the human gene for macrophage migration inhibitory factor (MIF) to chromosome 22q11.2 MIF plays a critical role in inflammatory diseases and atherogenesis. |
Synonyms | Macrophage migration inhibitory factor, Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, GLIF, MMIF |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Phenylalanine metabolism, Tyrosine metabolism |
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