Dhfr (C-term) Rabbit Polyclonal Antibody
Dhfr (C-term) rabbit polyclonal antibody
|Recommend Dilution||ELISA: 1/1,000.
Western blotting: 1/50 - 1/100.
|Immunogen||KLH conjugated synthetic peptide selected from the C-terminal region of mouse DHFR|
|Specificity||This antibody reacts to DHFR / DHFRP1.|
|Formulation||PBS with 0.09% (W/V) sodium azide
State: Liquid purified Ig
|Purification||Saturated Ammonium Sulfate (SAS) precipitation|
|Gene Name||Mus musculus dihydrofolate reductase (Dhfr)|
|Background||Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.|
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