Carboxypeptidase Z (CPZ) (N-term) Rabbit Polyclonal Antibody

CAT#: AP17239PU-N

Carboxypeptidase Z (CPZ) (N-term) rabbit polyclonal antibody

Product Images

Western blot analysis of CPZ Antibody (N-term) in K562 cell line lysates (35 ug/lane). CPZ (arrow) was detected using the purified Pab.

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  Formalin-fixed and paraffin-embedded human placenta with CPZ Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1:50 - 1:100.
  ELISA: 1:1,000.
  Immunohistochemistry on paraffin sections: 1:50 - 1:100.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human CPZ
• Specificity: This antibody detects CPZ at N-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: carboxypeptidase Z
• Database Link:
  Entrez Gene 8532 Human
  UniProt ID Q66K79
• Background: CPZ is a member of the metallocarboxypeptidase family. This enzyme displays carboxypeptidase activity towards substrates with basic C-terminal residues. It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases.
• Synonyms: CPZ
• Note: Molecular weight: 73627 Da

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein