AKAP9 Goat Polyclonal Antibody

CAT#: AP16328PU-N

Goat polyclonal anti-AKAP9 (C-term) antibody, Aff - Purified


 Product Datasheet for 'AP16328PU-N'

USD 380.00


Availability*
2 Weeks

Size
    • 0.1 mg


Product images

Specifications

Product Data
Recommend Dilution ELISA, IHC, WB
Reactivity Human, Mouse
Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence C-SGSTTQFHAGMR, from the C Terminus of the protein sequence
Formulation Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration 0,5 mg/ml
Purification Affinity chromatography
Predicted Protein Size ~0.5 kDa
Gene Name A-kinase anchoring protein 9
Background AKAP9 is a novel cytoskeletal protein specifically concentrated in the neuromuscular junction and neuronal synapes that interacts with specific splice variants of NMDA Receptor Subunit NR1 in a C1 exon cassette dependent manner. It has also been shown to physically attach the type I protein phosphatase (PP1) and the adenosine 3',5'-mono-phosphate (cAMP) dependent protein kinase (PKA) holoenzyme to NMDA receptors to regulate channel activity. NMDA receptors are involved with many important functions and dysfunctions of the nervous system, including synapse formation, synaptic plasticity, and excitotoxicity. AKAP9 research may lead to a clearer understanding of these neural processes by explaining how NMDA receptors are targeted to particular synapses, how this localization is regulated during development and synaptic activity, and how NMDA receptor activity is transduced into intracellular signals responsible for particular neuronal responses.
Synonyms AKAP-9; AKAP350; AKAP450; CG-NAP; HYPERION; LQT11; MU-RMS-40.16A; PPP1R45; PRKA9; YOTIAO
Reference Data
Protein Families Druggable Genome
Other products for "AKAP9"
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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