CLIC1 Rabbit Polyclonal Antibody

CAT#: AP14246PU-N

CLIC1 rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of anti-CLIC1 Antibody in A375 cell line lysates (35ug/lane). CLIC1 (arrow) was detected using the purified Pab (1:60dilution).

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  Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CLIC1 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
  Immunohistochemistry: 1/10 - 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a recombinant human CLIC1 protein.
• Specificity: This antibody reacts to CLIC1.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: chloride intracellular channel 1
• Database Link:
  Entrez Gene 1192 Human
  UniProt ID O00299
• Background: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
• Synonyms: NCC27, Chloride channel ABP, hRNCC

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other