RIP3 (RIPK3) (Center) Rabbit Polyclonal Antibody
Other products for "RIPK3"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | Immunohistochemistry on Paraffin sections: 1/10-1/50. |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide (aa 61-91) selected from the center region of human RIPK3. |
Specificity | This antibody detects RIPK3 / RIP3. |
Formulation | PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS |
Conjugation | Unconjugated |
Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | receptor interacting serine/threonine kinase 3 |
Database Link | |
Background | The product of the RIPK3 gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. |
Synonyms | RIP-3 |
Note | Molecular weight: 56901 Da. |
Reference Data |
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