RIP3 (RIPK3) (Center) Rabbit Polyclonal Antibody

CAT#: AP13847PU-N

RIP3 (RIPK3) (Center) rabbit polyclonal antibody, Purified


USD 560.00

2 Weeks*

Size
    • 400 ul

Product Images

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution

Immunohistochemistry on Paraffin sections: 1/10-1/50.
Western blot: 1/1000.
Enzyme immunoassay: >1/1000 (peptide elisa only)

Reactivities Human, Mouse
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide (aa 61-91) selected from the center region of human RIPK3.
Specificity This antibody detects RIPK3 / RIP3.
Formulation PBS with 0.09% (W/V) sodium azide
State: Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Conjugation Unconjugated
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name receptor interacting serine/threonine kinase 3
Background The product of the RIPK3 gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Synonyms RIP-3
Note Molecular weight: 56901 Da.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.