Gastrin (GAST) Rabbit Polyclonal Antibody
Rabbit polyclonal anti-Gastrin antibody, Serum
Product Datasheet for 'AP09558SU-N'
|Recommend Dilution||ICC/IF, IHC|
|Immunogen||Human gastrin 17 conjugated to BSA|
|Purification||Liquid Serum Serum|
|Predicted Protein Size||~9.2 kDa|
|Background||Gastrin is mainly known by its first described role as a gastric acid-hormone but the protein also has the ability to promote cellular growth. More recently, gastrin has been suggested to induce leukocyte-endothelial cell interactions and to have a pro-inflammatory effect. Gastrin has two biologically active peptide forms, G34 and G17 and they activate two different receptors: the CCK-1 receptor, which has low affinity for gastrin but high affinity for the related hormone cholecystokinin (CCK), and the CCK-2 receptor, which has high affinity for both gastrin and CCK and mediates the acid-secretory as well as the proliferative effects of gastrin.|
|Protein Families||Druggable Genome, Secreted Protein|
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