GFAP Rabbit Polyclonal Antibody

CAT#: AP08128PU-N

GFAP rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: Immunohistochemistry.
  Immunocytochemistry.
  Suitable for Frozen or Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections and cell smears: 1/50-1/200 using streptavidin~biotin system or polymer system.
  Recommended Positive Control:Human brain or astrocytoma.
• Reactivities: Bovine, Guinea Pig, Human, Mouse, Porcine, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Purified Human GFAP.
• Specificity: This antibody stains astrocytes, glial cells, ependymal cells and their corresponding tumors. In the peripheral nervous system , it stains Schwann cells, satellite and enteric glial cells.
  This antibody distinguishes neoplasm of astrocytes origin from other neoplasm of CNS.
  Cellular Localization: Cytoplasmic.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction
  Stabilizer: 1% BSA
  Preservative: 0.05% Sodium Azide
• Concentration: lot specific
• Purification: Protein A Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Predicted Protein Size: 51 kDa (Antigen)
• Gene Name: glial fibrillary acidic protein
• Database Link:
  Entrez Gene 14580 MouseEntrez Gene 24387 RatEntrez Gene 2670 Human
  UniProt ID P14136
• Background: Gilial Fibrillary acidic protein (GFAP), a 51 kDa an intermediate filament protein is closely related to non-epithelial family members, Vimentin, desmin and peripherin, which are all involved in structure and function of cell cytoskeleton. GFAP is expressed in central nervous system (CNS) in the astrocytes cells, functioning in cellular processes e.g. cell structure, movements, cell communication, brain processes and brain functions.
• Synonyms: Glial Fibrillary Acidic Protein

Reference Data

• Protein Families: ES Cell Differentiation/IPS