BACE2 Rabbit Polyclonal Antibody

CAT#: AP07871PU-N

Rabbit Polyclonal Anti-BACE2 Antibody, Purified


 Product Datasheet for 'AP07871PU-N'

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USD 480.00


Availability*
2 Weeks

Size
    • 50 ug

Product images

Specifications

Product Data
Applications IHC
Recommend Dilution IHC, WB
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic Peptide corresponding to Amino acids 44 to 59 of human BACE2 - KLH conjugated
Isotype IgG
Formulation PBS containing 0.02% Sodium Azide as preservative
Concentration 1,0 mg/ml
Purification Liquid purified IgG fraction
Purified
Predicted Protein Size 49.8KDa
Gene Name beta-site APP-cleaving enzyme 2
Background BACE2 (Memapsin 1) is a membrane-bound aspartic protease that is highly homologous with BACE1 (Memapsin 2). While BACE1 processes the amyloid precursor protein (APP) at a key step in generating the beta-amyloid peptide and presumably causes Alzheimer's disease (AD), BACE2 has not been demonstrated to be directly involved in APP processing, and its physiological functions remain to be determined. In vivo, BACE2 is expressed as a precursor protein containing pre-, pro-, protease, transmembrane, and cytosolic domains/peptides.
Synonyms AEPLC|ALP56|ASP1|ASP21|BAE2|CDA13|CEAP1|DRAP
Reference Data
Protein Families Transmembrane, Protease, Druggable Genome
Protein Pathways Alzheimer's disease
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.