Angiotensin Converting Enzyme 2 (ACE2) Rabbit Polyclonal Antibody

CAT#: AP05885PU-N

Angiotensin Converting Enzyme 2 (ACE2) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of human kidney lysate probed with Rabbit anti Human ACE2 antibody

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  Immunohistochemical staining of human kidney woth Rabbit anti Human ACE2 antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot.
  Immunohistochemistry on Paraffin Sections: Requires antigen retrieval using heat treatment prior to staining of paraffin sections.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a sequence within the amino terminus of Human ACE2.
• Specificity: This antibody is specific for Angiotensin-converting enzyme 2 (ACE2).
• Formulation: PBS
  State: Purified
  State: Liquid purified Ig fraction
  Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: angiotensin I converting enzyme 2
• Database Link:
  Entrez Gene 59272 Human
  UniProt ID Q9BYF1
• Background: ACE2 is a carboxypeptidase which is expressed in a range of tissues including heart, kidney, testis and the gastrointestinal system.
  ACE2 is a homologue of ACE (Angiotensin-converting enzyme 1), although it has a distinct catalytic activity. ACE2 catalyzes the cleavage of active angiotensin II into angiotensin 1-7, which may counteract the effects of ACE by increasing vasodilatation.
  A recent discovery is that ACE2 serves as the cellular entry point for the severe acute respiratory syndrome (SARS) virus, functioning as a receptor for the SARS Spike protein.
• Synonyms: Angiotensin-converting enzyme 2