CTBP1 Rabbit Polyclonal Antibody

CAT#: AP03000PU-N

CTBP1 rabbit polyclonal antibody, Aff - Purified

Specifications

Product Data

• Applications: IF, IP, WB
• Recommended Dilution: Immunoprecipitation.
  Western Blotting (Reducing conditions).
  Immunocytochemistry (1 μg/ml): acetone/methanol fixation.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Bacterially expressed recombinant human CtBP1.
• Specificity: The polyclonal antibody reacts with CtBP1, a 49 kDa transcriptional corepressor, that plays a critical role in regulating gene expression.
• Formulation: PBS, pH 7.4 with 15 mM sodium azide as preservative.
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
• Concentration: lot specific
• Purification: Protein-A affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens C-terminal binding protein 1 (CTBP1), transcript variant 1
• Database Link:
  Entrez Gene 13016 MouseEntrez Gene 1487 Human
  UniProt ID Q13363
• Background: C-terminal binding protein 1 / brefeldin A (BFA)-dependent ADP-ribosylation substrate (CtBP1/BARS) is a highly conserved transcriptional corepressor, that plays a critical role in regulating gene expression patterns throughout development and in oncogenesis. CtBP regulates target gene transcription, in part, via recruitment of histone deacetylases involved in gene silencing and may act to coordonate histone modifications that regulate gene expression.
• Synonyms: C-terminal-binding protein 1, CTBP

Reference Data

• Protein Pathways: Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway