AKT2 Rabbit Polyclonal Antibody
Other products for "AKT2"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | Suitable for use in Western blot (1:500-1:1000) and Immunohistochemistry (1:50-1:100). |
Reactivities | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against synthesized non-phosphopeptide derived from human Akt2 around the phosphorylation site of serine 474 (Q-F-Sp-Y-S). |
Specificity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Akt2 antibody AP02678PU detects endogenous levels of total Akt2 protein. |
Formulation | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol. State: Aff - Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Immunoaffinity chromatography. |
Conjugation | Unconjugated |
Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Database Link | |
Background | The serine/threonine kinase Akt (protein kinase B or PKB) has a central role in the regulation of several signaling pathways controlling cell proliferation, apoptosis, angiogenesis, and diabetes. In humans, there are three genes in the "Akt family": Akt1, Akt2, and Akt3. AKT2 is a putative oncogene and is a general protein kinase capable of phophorylating several known proteins. AKT2 is amplified and overexpressed in some human carcinomas. AKT2 acts primarily as a regulator of glucose metabolism. |
Synonyms | RAC-PK-beta, Protein kinase Akt-2, Protein kinase B beta |
Reference Data |
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