BCL2 pThr56 Rabbit Polyclonal Antibody

CAT#: AP01537PU-N

BCL2 pThr56 rabbit polyclonal antibody, Aff - Purified

Product Images

Immunohistochemistry (IHC) analysis of p-BCL-2 (pThr56) antibody Cat.-No.: AP01537PU-N in paraffin-embedded human breast carcinoma tissue.

Specifications

Product Data

• Applications: IF, IHC, IP, WB
• Recommended Dilution: Western Blot: 1/500-1/200.
  Immunoprecipitation: 1/50-1/200.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
  Immunofluorescence: 1/50-1/200.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of BCL-2 protein only when phosphorylated at Thr56.
• Formulation: Phosphate Buffered Saline (PBS), pH~7.2 with 0.05% Sodium Azide as preservative.
  State: Aff - Purified
  State: Liquid purified Ig fraction is (> 95% pure by SDS-PAGE).
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~26 kDa
• Gene Name: B-cell CLL/lymphoma 2
• Database Link:
  Entrez Gene 596 Human
  UniProt ID P10415
• Background: Bcl2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of Bcl2, such as in the case of translocation of Bcl2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C terminal ends.
• Synonyms: BCL2, Bcl-2 alpha