CysLT1 (CYSLTR1) Rabbit Polyclonal Antibody

SKU AP01264PU-N

CysLT1 (CYSLTR1) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IF, WB
• Recommended Dilution: Western blot: 1/500-1/1000.; Immunofluorescence: 1/50-1/200.
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 139-188 of Human CysLTR1.
• Specificity: This antibody detects endogenous levels of CYSLTR1 protein (region surrounding Lys172).
• Buffer: Phosphate buffered saline (PBS), pH~7.2; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: ~ 38 kDa
• Gene Name: cysteinyl leukotriene receptor 1
• Database Link:
  Q9Y271
• Background: Cysteinyl leukotriene (CysLTs) induce intracellular calcium mobilization through the binding of two distinct seven-transmembrane, G protein-coupled receptors, designated CysLT1 and CysLT2 receptors, to induce potent broncoconstriction. Airway smooth muscle and macrophages express both receptor types, and additionally monocytes and eosinophils express CysLT1 receptor, while cardiac Purkinje cells, adrenal medulla, peripheral blood leukocytes and brain also utilize CysLT2 receptor. The effects of the CysLT receptors can be blocked by antagonists, indicating a therapeutic mechanism for the treatment of asthma and allergies.
• Synonyms: Cysteinyl leukotriene receptor 1, CysLTR1, LTD4 receptor, HG55, HMTMF81

Reference Data