Adenosine Receptor A2a (ADORA2A) Rabbit Polyclonal Antibody

CAT#: AP01259PU-N

Reviews ()
Write a review

Adenosine Receptor A2a (ADORA2A) rabbit polyclonal antibody, Aff - Purified


 Product Datasheet for 'AP01259PU-N'

USD 370.00


Availability*
2 Weeks

Size
    • 100 ug


Product images

Specifications

Product Data
Applications ELISA, IF, IHC, WB
Recommend Dilution Western Blot: 1/500-1/1000.
Immunofluorescence: 1/50-1/200.
Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 330-380 of Human ADORA2A.
Specificity This antibody detects endogenous levels of Adenosine A2A-R protein. (region surrounding Tyr361)
Formulation Phosphate buffered saline (PBS), pH~7.2
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Preservative: 0.05% Sodium Azide
Concentration 1.0 mg/ml
Purification Affinity Chromatography using epitope-specific immunogen
Predicted Protein Size ~45 kDa
Background Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis. The adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.
Synonyms ADORA2A, ADORA2
Reference Data
Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Antibody Performance Guarantee banner
ANTIBODY VALIDATION 101
BOGO Free lysates
68 Mouse Clones