5HT5A receptor (HTR5A) Rabbit Polyclonal Antibody

CAT#: AP01244PU-N

5HT5A receptor (HTR5A) rabbit polyclonal antibody, Aff - Purified


USD 464.00

3 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Applications IF, WB
Recommended Dilution Western Blot: 1/500-1/1000.
Immunofluorescence: 1/50-1/200.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 200-250 of Human SR-5A.
Specificity This antibody detects endogenous levels of SR-5A protein. (region surrounding Pro241)
Formulation Phosphate buffered saline (PBS), pH~7.2
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
Preservative: 0.05% Sodium Azide
Concentration 1.0 mg/ml
Purification Affinity Chromatography using epitope-specific immunogen.
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: One year from despatch.
Predicted Protein Size ~40 kDa
Background SR-5B, also designated 5-hydroxytryptamine (Serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134) is a receptor for the monoamine ligand Serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with Serotonin transporter mRNA is high in the intermediate portions of the nucleus. Serotonin receptors include SR-1-7 (5HT1-7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Subtypes within the SR-2 group include SR-2A, -2B and -2C. Subtypes within the SR-5 group include SR-5A and -5B.
Synonyms 5-hydroxytryptamine receptor 5A, 5-HT5A, 5-HT-5A, 5-HT-5
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.