AP2 gamma (TFAP2C) Rabbit Polyclonal Antibody

CAT#: AP01241PU-N

AP2 gamma (TFAP2C) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of AP-2 gamma antibody in extracts from HepG2 cells.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunhistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 400-448 of Human AP-2γ.
• Specificity: This antibody detects endogenous levels of AP-2 gamma protein. (region surrounding Ala436)
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Predicted Protein Size: ~45 kDa
• Database Link:
  Entrez Gene 7022 Human
  UniProt ID Q92754
• Background: AP2 gamma is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
• Synonyms: Transcription factor AP2 gamma, ERF-1, ERF1