IL7R alpha (IL7R) Rabbit Polyclonal Antibody

CAT#: AP01223PU-N

IL7R alpha (IL7R) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of IL-7R antibody in extracts from K562 cells treated with insulin 0.01U.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 410-460 of Human IL7R.
• Specificity: This antibody detects endogenous levels of IL-7R protein. (region surrounding Gln445)
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Predicted Protein Size: ~52 kDa
• Database Link:
  Entrez Gene 3575 Human
  UniProt ID P16871
• Background: The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. The functional high-affinity IL7 receptor consists of an alpha chain and a gamma chain. Both IL7R alpha and IL7R gamma are members of the hematopoietin receptor superfamily. IL7R alpha cDNA encodes a precursor protein containing a signal peptide, an extracellular ligand binding domain, a transmembrane region, and a cytoplasmic region. IL7R alpha transcripts have been observed in spleen, thymus, fetal liver, developing T cells, B cells, mature T cells, and bone marrow derived macrophages.
• Synonyms: Interleukin-7 receptor subunit alpha, IL-7R-alpha, IL7 receptor alpha