IL7R alpha (IL7R) Rabbit Polyclonal Antibody
Other products for "IL7R"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western Blot: 1/500-1/1000. |
Reactivities | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to amino acids 410-460 of Human IL7R. |
Specificity | This antibody detects endogenous levels of IL-7R protein. (region surrounding Gln445) |
Formulation | Phosphate buffered saline (PBS), pH~7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE). Preservative: 0.05% Sodium Azide |
Concentration | 1.0 mg/ml |
Purification | Affinity Chromatography using epitope-specific immunogen. |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Predicted Protein Size | ~52 kDa |
Database Link | |
Background | The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. The functional high-affinity IL7 receptor consists of an alpha chain and a gamma chain. Both IL7R alpha and IL7R gamma are members of the hematopoietin receptor superfamily. IL7R alpha cDNA encodes a precursor protein containing a signal peptide, an extracellular ligand binding domain, a transmembrane region, and a cytoplasmic region. IL7R alpha transcripts have been observed in spleen, thymus, fetal liver, developing T cells, B cells, mature T cells, and bone marrow derived macrophages. |
Synonyms | Interleukin-7 receptor subunit alpha, IL-7R-alpha, IL7 receptor alpha |
Reference Data |
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