CysLT2 (CYSLTR2) Rabbit Polyclonal Antibody

CAT#: AP01211PU-N

CysLT2 (CYSLTR2) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of CysLTR2 antibody in extracts from HeLa cells.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunofluorescence: 1/50-1/200.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 290-336 of Human CysLTR2.
• Specificity: This antibody detects endogenous levels of CysLTR2 protein. (region surrounding Lys322)
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Predicted Protein Size: ~ 40 kDa
• Gene Name: cysteinyl leukotriene receptor 2
• Database Link:
  Entrez Gene 57105 Human
  UniProt ID Q9NS75
• Background: The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, CysLT2 and CysLT1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. CysLT2 expression has been reported in adrenal medulla, blood, brain, heart, kidney, lung, lymph node, ovary, placenta, prostate, pulmonary artery and vein, small intestine, and spleen.
• Synonyms: Cysteinyl leukotriene receptor 2, CysLTR2, CYSLT2, HG57, HPN321, hGPCR21