QK1 (QKI) Mouse Monoclonal Antibody [Clone ID: S147-6]
Mouse Monoclonal Anti-QKI Antibody, Purified
Product Datasheet for 'AM60063PU-N'
|Recommend Dilution||ICC/IF, IHC, WB|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Fusion protein amino acids 1-341 (full-length) of human QKI-5 (accession number Q96PU8, isoform 1) with >90% identity with QKI-6, QKI-7 and QKI-7b.|
|Formulation||PBS pH 7.4, 50% Glycerol,? 0.09% Sodium azide|
|Purification||Protein G chromatography|
|Predicted Protein Size||37.5 kDa|
|Gene Name||QKI, KH domain containing, RNA binding|
|Background||QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients. Several isoforms are known.|
|Synonyms||Hqk; QK; QK1; QK3; hqkI|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.